Director Of Pharmacometrics

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You will have the opportunity to: Develop and execute innovative modelling simulation (MS) strategic plans for projects in various disease areas and different stages of product development. Develop (population) pharmacokinetic and (population) pharmacodynamic models and apply empirical and/or mechanistically-based drug disease models. Conduct simulations to inform drug development decisions such as starting dose, efficacious dosage regimen selection and other aspects of trial design. Communicate the outcome of MS analysis to project teams to support decision making. Contribute to responses to health authority requests and interactions. Collaborate with partners in project team(s) regarding all aspects of MS to appropriate integration of MS strategy and results into internal and external project documents (e.g. Clinical Development Plan, Investigator Brochure, NDA documents).Requirements PhD, PharmD, Msc or MD (in natural sciences, mathematics, physical sciences or engineering) 10+ years experience in clinical drug development and 7+ years planning and conducting MS projects for clinical study data. Strategic mindset and clear vision of how and when MS can contribute value in drug development. Significant experience with MS software (e.g. NONMEM, Monolix, Phoenix, MATLAB, Gastroplus, Simcyp, SAS, R, etc.). Keen interest in technological advances (e.g. Bayesian modelling). Ability to influence and lead without authority in a matrix organisation and strong written and oral communication.Benefits Join our inclusive, collaborative and intellectually stimulating organisation with strong company values. As a learning organisation, we provide access to learning and development opportunities and will place you at the forefront of your career growth at Exscientia. We employ brilliant people so we pay highly competitive salaries. Additionally, all our employees are eligible for a company-wide annual bonus and receive both a new joiner and annual share award. Enjoy our generous holiday allowance and flexible working approach to find a healthy work-life balance that works for you. Create amazing memories or progress your personal and professional development with our four-week paid sabbatical after four years of service. Were leading the way in progressive leave, offering enhanced policies such as generous parental leave, surrogacy, menopause, and family emergency leave so you feel supported no matter the life event. Additionally, we support childcare costs for children aged 0-5 through our affordable childcare scheme. Take advantage of two generous salary exchange schemes to claim discounts on a brand new electric vehicle and cycling equipment worth up to £3,500. As a healthcare company, we understand the importance of health and wellbeing so we provide comprehensive private health insurance, dental and vision benefits for you and your family. We also provide plenty of access to mental health support including therapy and counselling sessions plus an employee assistance program for help with lifestyle issues such as bereavement, family problems or money management. To help safeguard the future for you and your loved ones, we also offer pension and life cover. Help yourself to free drinks and snacks in our fully stocked kitchens. Join your colleagues in one of our many breakout areas and get to know the people you are working with. Some of the best ideas start with a coffee break! Feel inspired in our high spec labs where you will use state-of-the-art equipment and instrumentation that enable you to do your best work. Well even support your home office environment with an allowance for furniture and equipment to make your space as comfortable and productive as possible.Please use the below link for job application and quicker response.https://lifelancer.com/jobs/view/57ea2e27ffb66668a71ccf1a3f834b47

29 April 2024
Location: United Kingdom Oxford
Work type:
Full time
PLEASE! No enquiries from Recruitment Agencies or Headhunters.

Only direct applications will be considered.

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